clamwin creates the following report each (and every) time it runs:

Infected files: 1
Not moved: 1
Data scanned: 7838.86 MB
Time: 4589.068 sec (76 m 29 s)
--------------------------------------
Scan started: Thu Feb 2 14:00:01 2006

File excluded 'C:\Documents and Settings\All Users\.clamwin\quarantine\Dc45.exe'
ERROR: Can't open file C:\Program Files\Common Files\Symantec Shared\CCPD-LC\symlcrst.dll
ERROR: Can't open file C:\WINDOWS\system32\config\default
ERROR: Can't open file C:\WINDOWS\system32\config\SAM
ERROR: Can't open file C:\WINDOWS\system32\config\SECURITY
ERROR: Can't open file C:\WINDOWS\system32\config\software
ERROR: Can't open file C:\WINDOWS\system32\config\system

C:\Documents and Settings\All Users\.clamwin\quarantine\Dc45.exe: Adware.NewDotNet.B-4 FOUND
-- summary --
Known viruses: 43959
Engine version: 0.88
Scanned directories: 3109
Scanned files: 46846
Infected files: 1
Not moved: 1
Data scanned: 7882.10 MB
Time: 5014.707 sec (83 m 34 s)


need help on what to do about it

you can ignore ERROR: Can't open file... lines these are files that are lokced and can't be read.
you can simply remove Dc45.exe from C:\Documents and Settings\All Users\.clamwin\quarantine folder, however be sure to empty your recycle bin afterwards