Here is a batch file to scan just one file.

e.g onescan.bat

echo off
echo calling ClamWinPortable to scan : %1
clamwinportable --mode=scanner --path=%1

Put it in your ClamWinPortable folder and create a shortcut to it.
Move the shortcut to your SendTo folder.

You can now right-click any file > SendTo for a quick scan.

Well, thanks humpty, but ClamWin Portable is a different open sourced project and not supported in these forums AFAIK. You will likely reach a greater number of ClamWin Portable users by posting at PortableApps (creator of ClamWin Portable) at https://portableapps.com/forums/support/clamwin_portable Still, I will find your bat file useful for some situations. Thanks again.

Note: I believe that when a portable program integrates with the Windows shell (context menu in this case) it is no longer considered portable.

I just joined because of this. I've been looking for a working SendTo shortcut for years, and this is it. Thank goodness there's a latest 2013 tip. I tried using the tips from posts from the net from older years, but nothing worked right. I changed the line: clamwinportable --mode=scanner --path=%1 to clamwin --mode=scanner --path=%1 to work for my non-portable ClamWin. I added the @ sign to tidy the messages displayed on the DOS box. I placed the batch file inside of the bin folder.

My batch file looks like this now:
@echo off
echo Scanning: %1
clamwin --mode=scanner --path=%1

I found out that such a batch file can also scan a folder recursively. I hope there would be a similar tip on how to scan multiple-highlighted files too.

Thank you very much for the tip! Even though it was originally meant for a portable edition, it can still be used with the original non-portable one. Please don't delete this thread as I know a lot of other people will benefit as well.