Most likely it's a false positive if you've had/used the file/program for a time. Upload the file (if you can) to Jotti at http://virusscan.jotti.org/
on line, and they will provide a free scan of it with 20 antiviruses including ClamAV. If at least four or five antiviruses find malware, it is probably for real, and, in that case, contact the vendor before you do anything.
I recently had a ClamWin false positive for another antivirus program! FPs happen with all AVs from time to time. Viruses do many of the same things that normal software does--upload, download, change the registry, etc. That's why I configure ClamWin to Report only and not to quarantine--I don't want it to quarantine an important system file and lose access to the system.